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Critically, inactivating these genes also prevented lifespan extension through other known strategies, such as dietary restriction and inhibiting the cellular organelle responsible for producing energy

Espah Borujeni A, Salis HM

Its also important to note that these peptides are not mutually exclusive

10.1096/fj.202101567R 53 DrommiM.RulmontC.EsmieuC.HureauC

Despite current limitations highlighted in this review, implementing appropriate controls and recommendations from the metabolomics community will make this field move forward improving the overall quality and comparability of the data which is required for drug screening purposes
