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Critically, inactivating these genes also prevented lifespan extension through other known strategies, such as dietary restriction and inhibiting the cellular organelle responsible for producing energy

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Espah Borujeni A, Salis HM

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Its also important to note that these peptides are not mutually exclusive

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10.1096/fj.202101567R 53 DrommiM.RulmontC.EsmieuC.HureauC

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Despite current limitations highlighted in this review, implementing appropriate controls and recommendations from the metabolomics community will make this field move forward improving the overall quality and comparability of the data which is required for drug screening purposes

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