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10.1186/1472-6882-1-7 [DOI] [PMC free article] [PubMed] [Google Scholar] 22.Nijs J, Elma , Yilmaz ST, Mullie P, Vanderween L, Clarys P, Malfliet A

Particularly, animal studies showed both systemically and locally increased nitric oxide synthase (NOS) expression in leaflet areas showing myxomatous degeneration, therefore suggesting a possible role of nitric oxide in MVP pathogenesis (45)

At a structural level, research highlighted several features linked to methylene blue that may give it an advantage: Small molecular weight with both hydrophilic and lipophilic properties, which may help it move through different tissues once absorbed

Gastrointestinal permeability in celiac disease

doi:10.1186/1743-7075-7-30