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A striking illustration of gutbrain neural connectivity is seen in PD: misfolded -synuclein protein aggregates, a hallmark of PD, are hypothesized to originate in the gut and spread to the brain via vagal nerve fibers in a prion-like fashion [31]
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doi: 10.1161/01.HYP.0000171472.24422.33 74 SantiagoJJDangerfieldALRattanSGBatheKLCunningtonRHRaizmanJEet al
