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Critically, there is no rigorous, comparative research to definitively prove the methods are equally effective or interchangeable

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doi: 10.1038/jid.2009.32 85 MansuriMSSinghMJadejaSDBegumR

In some cases, injection near the affected tissue may be considered

The continued treatment with 1 M was done as this concentration is within range of the serum concentrations of the sum of tamoxifen and its metabolites in breast cancer patients treated with tamoxifen [24]