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To investigate whether ABCC1 overexpression can drive resistance to BCL-2 inhibition, we used HL-60 cells that were engineered to ectopically express ABCC1 (Fig

E., Bahri F., Fooladi S., et al

The researchers found that patients taking chlorthalidone had nearly three times the risk of developing dangerously low levels of potassium and a greater risk of other electrolyte imbalances and kidney problems compared with those taking hydrochlorothiazide

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