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Altogether, these findings suggest that certain -KG competitors including DM-succinate and ITA recapitulate -KG insufficiency to inhibit the YBX1AMPK axis in human cells, reinforcing the importance of -KG as an epigenetic cofactor for energy sensing

10.1136/gutjnl-2013-305302 62

Identification of a novel small-molecule binding site of the fat mass and obesity-associated protein (FTO)

Site-directed, ligase-independent mutagenesis (SLIM): a single-tube methodology approaching 100% efficiency in 4 h
