glutathione s-transferase function - an overview Frontiers | Glutathione S-Transferases: Role

Patients with certain variants may show higher baseline inflammatory markers or slower adaptation to rapid metabolic change

Probiotic administration reduces intestinal leakage by, among others, affecting intestinal immunoregulation and anti-inflammatory effects (for example, an increase in sIgA production), anti-inflammatory effects, strengthening the epithelial barrier (for example, an increase in the synthesis of mucin and short-chain fatty acids (SCFAs), and the production of bacteriocins, which limit the growth of pathogenic microorganisms (for example, defensin) [8, 133, 134]

doi: 10.1016/j.trac.2020.115876 180

Anyone selling you a precise human bioavailability figure is guessing

And for some people who have HIV, or even for people who don't have HIV, the deposits of visceral fat can be problematic for their health