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The skin lesions had changed, becoming smoother and even paler (Figures 11 and 12)

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Particularly, mitogen-activated protein kinase (MAPK) signaling pathway is involved, resulting in a wide range of fundamental cellular process variations, including cell growth, differentiation, survival, apoptosis, migration, inflammation, and response to environmental stresses

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Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity