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Below, tips from our experts on things you can do to avoid pigmentation from darkening in that sensitive area: Avoid too-tight clothing: Looser clothes and breathable fabric will help prevent excessive sweating and irritation, two things that can cause darkening to occur, says Emer

doi:10.1016/j.amjoto.2012.06.009

Recently we used the BDL model in mice and showed that hepatic expression of GSH synthetic enzymes increased early on likely as an adaptive response to oxidative stress but decreased markedly along with GSH levels during later stages of BDL [136]

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