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Journal of Orthopaedic Research , 2010

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Distinction From Other Mitochondrial Peptides While Humanin primarily protects against cell death in neural and cardiac models, MOTS-C peptide broadly enhances metabolic homeostasis by targeting AMP-activated protein kinase, or AMPK, and antioxidant pathways

[DOI] [PubMed] [Google Scholar] 34.Ma Y., Wang Q., Zhu Q., Liu M., Chen D., Han Z., Zhang C., Lv L., Gu Y

its rapidly depleted by constant illness, inflammation, and stress
