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Neurochem Int 22: 1929

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doi: 10.2165/00129785-200505030-00002

Details of the hepatocellular and biochemical mechanisms responsible for the metabolic channeling of cholesterol toward cholic acid versus chenodeoxycholic acid/6-hydroxylated bile acids are still not clear, and the specificity is not absolute

However, the mouse model does not mimic the classic male renal phenotype because only small-fiber neuropathy and hypertrophic cardiomyopathy are the key features of the model 6,34