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The Greenland shark can live up to a mind blowing 500 years old, and it is hoped their longevity could hold the key to anti-ageing in humans

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10.1038/s41581-019-0129-4 43 RonauJ

These abnormalities were previously regarded as secondary epiphenomena of metabolic dysfunction, but accumulating evidence now indicates that they arise from hyperglycaemia-driven OCTN2 impairment, insulin resistance, and oxidative stress, together forming a distinct carnitine-related metabolic signature