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doi: 10.3389/fcvm.2025.1636090 Received 27 May 2025 Revised 29 November 2025 Accepted 15 December 2025 Published 06 January 2026 Volume 12 - 2025 Edited by Xiaofeng Yang, Temple University, Philadelphia, United States Reviewed by Dotan Shaniv, Kaplan Medical Center, Israel Chongzhuang Tang, XenoFinder Co LTD, China Updates Copyright 2026 Li, Qu, Li and Li