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Description

Synergistic effects of combination therapy with anti-EGFR and anti-Src therapy in vitro in colon cancer, 2007

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What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

This innovative delivery system not only addresses the challenges associated with the difficulty of mRNA crossing cell membranes and its susceptibility to nuclease degradation in vivo but also plays a crucial role in ensuring the stability and efficacy of mRNA vaccines