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Description
The NAD + /NADH redox pair modulates gene expression through redox-sensitive transcription factors [9], acts as a precursor of multiple NAD + -dependent enzymes involved in synaptic plasticity and neuronal stress resistance, and regulates crucial signaling pathways related to neuronal survival [10]

& Swain, M

FGF21 has originally been described as a fasting hormone that is upregulated in the liver via PPAR and partly regulates ketogenesis during starvation or KDs

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M.GedaY
