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Gating strategies are shown in Supplementary Fig

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In vivo and in vitro regulation of erythropoietin mRNA: measurement by competitive polymerase chain reaction

[46] Once bound, -arrestins both sterically prevent G-protein coupling and may recruit other proteins, leading to the creation of signaling complexes involved in extracellular-signal regulated kinase (ERK) pathway activation or receptor endocytosis (internalization)

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