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Recently, it has been found that almost all organs, tissues and cells tested have the ability to synthesize melatonin using the same pathway and enzymes the pineal uses [25,26]

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OCTN1 and OCTN2 are also functionally expressed within dorsal root ganglia neurons, and OCTN1 is thought to be the main contributor to the neuronal accumulation of oxaliplatin and a mediator of its neurotoxicity [4, 6,7,8]

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