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These findings underscore the developmental importance of early microbial signals in shaping neural circuits and behavior, processes modulated by molecules such as reelin, which controls dendritic growth and synaptic receptor function in post-natal entorhinal cortex neurons (Leifeld et al., 2022)

RNS includes peroxynitrite-nitrosoperoxycarbonate is produced when peroxynitrite and carbon dioxide react with nitric oxide (NO) (37)

In addition, carnosine can also inhibit the activity of cyclooxygenase-2, reduce the production of prostaglandins and further alleviate the inflammatory response (82)

Design and fabrication of 3D-printed anatomically shaped lumbar cage for intervertebral disc (IVD) degeneration treatment