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Reactive oxygen species act through p38 mapk to limit the lifespan of hematopoietic stem cells

Non-transferrin-bound iron (NTBI) can enter cells via the zinc transporters ZIP8 (SLC39A8) and ZIP14 (SLC39A14) [20,21], while iron bound to the extracellular matrix polysaccharide, hyaluronan, is proposed to bind CD44, with the resulting complex being taken up by endocytosis [22]

Skobowiat C, Slominski AT

[DOI] [PubMed] [Google Scholar] 10.Kaur G., Gupta S.K., Singh P., Ali V., Kumar V., Verma M