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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults

The signalling function of lactate dehydrogenase remains a matter of discussion (227), but DAMPS sensu strictu such as HMGB1, eATP and cytoplasmatic and extracellular dsDNA prime the immune system for stronger responses to current and upcoming threats

Nat Rev Rheumatol (2016) 12(7):38597

Inhibition of xCT suppresses the efficacy of anti-PD-1/L1 melanoma treatment through exosomal PD-L1-induced macrophage M2 polarization

Runx2 plays a critical role in the early stages of osteoblast differentiation, guiding mesenchymal stem cells (MSCs) through the activation of osteogenic-specific genes such as osteocalcin (OCN), osteopontin (OPN), and bone sialoprotein (BSP) (75)