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doi: 10.1152/ajpcell.00139.2004 56 Vander HeidenMGCantleyLCThompsonCB

TB-500s biological activity is mediated primarily through binding of the LKKTETQ actin-binding motif to G-actin and sequestering actin monomers, regulating actin polymerisation dynamics, and activating downstream signalling through the PI3K/Akt pathway that promotes cell survival, migration, and proliferation in multiple cell types relevant to tissue repair including endothelial cells, fibroblasts, keratinocytes, and myocytes

International Regulatory Harmonization International harmonization efforts have improved the efficiency of peptide drug development across multiple markets
"I had some real hope that we were going to be rescued, but sadly no," Butterfield said

Disorders of Hair Growth: Diagnosis and Treatment