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First, the use of rhenium(I) tricarbonyl [Re(CO) 3 ] scaffold in biomedicine is attractive due to its low spin d 6 electron configuration, octahedral geometry for variable coordination, kinetic inertness as a result of strong-field ligands, and photophysical properties that allow for excited triplet state transitions

As an allosteric positive regulator of ICDH, a decrease in AMP leads to excretion of citrate from the mitochondria

Wang J, Byrne JD, Napier ME, Desimone JM

References Akcali A, Zengin F, Aksoy SN (2017) Fatigue in multiple sclerosis: is it related to cytokines and hypothalamic-pituitary-adrenal axis

Dex has shown potential in augmenting cognitive function post-surgical anesthesia, likely by bolstering the expression of cyclooxygenase (COX), which not only protects the mitochondrial respiratory chain but also regulates mitochondrial energy metabolism [54]