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Dopamine oxidation, through the endogenous production of various neurotoxic metabolitessuch as dopamine quinones and thio-catecholaminestriggers a cascade of molecular events leading to cell death, with a high specificity for dopaminergic neurons in the substantia nigra

Gut Microbiome as a Modulator of Oxidative Stress and Inflammation Recent advances identify the gut microbiome as a promising therapeutic target to break the cycle of oxidative stress and inflammation in chronic and metabolic diseases

Erdosteine contains 2 blocked sulfhydryl groups that after first pass metabolism are converted to 3 metabolites with mucoactive and antioxidant properties that can scavenge free radicals

Myeloid cell PKM2 deletion enhances efferocytosis and reduces atherosclerosis

The New York Daily News