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Plain glutathione delivered to the plasma by precursors, liposomal products or intravenously must be broken down by enzymes to the basic amino acid components for absorption into the cell and require more energy expenditure to be re-constructed back to rGSH

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This is particularly true of conventional oncological treatment cancer-related exhaustion, also known as cancer fatigue, is the result of the impact of chemotherapy and radiation therapy and often leads to a weakening of the bodys defences