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2021 May 26;16(5):e0251578
Furthermore, the cell membrane-coated ZIF-8@MnOx nano-platform mPDZM simultaneously loaded with doxorubicin and piperlongumine can effectively promote CD8 + T cell and NK cells infiltration by regulating SASP release, inducing ICD and activating the STING signaling pathway, while reducing Tregs and M2-like macrophages and can further enhance anti-tumor immunity and produce a strong abscopal effect on distant tumors when combinated with anti-PD-L1 therapy (235)
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Figure 3 ( 2+ sensitive enzymes that respond to elevated intracellular levels of Ca 2+ which are present during muscle contraction
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis
