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Protocatechuic acid attenuates osteoclastogenesis by downregulating JNK/c-Fos/NFATc1 signaling and prevents inflammatory bone loss in mice
Mean reductions in hemolytic markers were observed as well
However, in marked contrast to previous in vivo studies 33,34 , CB-839 administration to KP and KPH2 animals substantially inhibited tumour growth, as calculated from the difference in the muscular compartment of tumour-bearing limbs (red) relative to control limbs (green) (Fig
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