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Hydrogen nutrition therapy application in brain and nervous system diseases The brain abundantly produces ROS, which can cause neurological disorders, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis [92]

Solute Carrier Family 7 Member 11 (SLC7A11, xCT), a cystine transporter, is often highly expressed in tumor cells, which not only participates in the synthesis of glutathione (GSH), but also plays an indispensable role in the inhibition of oxidative stress-induced ferroptosis

Anal Biochem 239(1):7076
The elimination of the nitrite gives the nitroalkene, while the reduction of the peroxide into an alkoxyl radical gives a nitro-hydroxy metabolite by reduction of a nitro-oxo metabolite by oxidation (Scheme 46)

Serum thioredoxin reductase levels increase in response to chemically induced acute liver injury
