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Description
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Additionally, several other SNPs, including in CAMKK1 (Calcium/Calmodulin Dependent Protein Kinase 1, involved in regulation of apoptosis), CYP2C8 (Cytochrome P450 Form 1) and CYP2C9 (Cytochrome P450 PB-1, both involved in hepatic drug clearance), NFATC2 (Nuclear Factor of Activated T-Cells 2), ID3 (Inhibitor Of Differentiation 3) and SLC10A2 (apical sodium-dependent bile acid transporter) have been suggested to be involved in vincristine-induced neuropathy (Johnson et al., 2011)
What About Joint and Bone Health
These enzymes share the same functions, but NDH-2 does not contribute to the generation of the transmembrane proton gradient
HAS2 is more active than HAS1, and its upregulation is involved in wound healing, inflammation, and tissue growth
