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(PubMed) Parente E, Colannino G, Picconi O, Monastra G

Kopetz S , Grothey A, Van Cutsem E, Yaeger R, Wasan H, Yoshino T, Desai J, Ciardiello F, Gollerkeri A, Maharry K, Loupakis F, Hong Y, Steeghs N, Guren T, Arkenau H, Garca Alfonso P, Sandor V, Christy-Bittel J, Anderson L, Tabernero J

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Although strengths of this study include the large sample size and the use of narrow age categories, limitations include confounders such as age-related changes in embryos independent of ploidy and the lack of information about uterine pathologies which may be more common with age and which may interfere with embryo implantation