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[DOI] [PMC free article] [PubMed] [Google Scholar] 204.Huang W., Hickson L.J., Eirin A., Kirkland J.L., Lerman L.O

& Mandrekar, P

Kidney diseases, specifically acute kidney injury (AKI) and chronic kidney disease (CKD), represent major global health burdens.3,4 The pathophysiology of these renal diseases involves interconnected mechanisms, notably inflammation, fibrosis, and oxidative stress, with the excessive generation of reactive oxygen species playing a critical role in disease initiation and progression.5,6 Consequently, therapeutic strategies that modulate oxidative stress and associated redox-sensitive signaling pathways are increasingly relevant to nephrological research and clinical practice

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Ringel and Maharshak, 2013