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doi: 10.1016/j.conb.2023.102798 42
Both the treatment and placebo groups showed significant symptomatic improvement

Tranexamic Acid Mesotherapy Vitamin C + Glutathione co-actives Dermal injection Trusted Results: Clinically proven melanin pathway suppression most effective for hormonal melasma where topicals and surface peels have not sustained results

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All of these limitations are relevant to HGF
