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Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse diet-induced obesity in mice. Nature Medicine, 25(11), 17611771
The compound's selectivity extends to its membrane permeability characteristics, which allow efficient cellular uptake without affecting membrane integrity or cellular viability up to 100 M concentrations
Identification of nicotinamide N-methyltransferase as a promising therapeutic target for sarcopenia
Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
