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Testing began 1 week after the sciatic nerve repair surgery was conducted and occurred at weekly intervals
Alterations of gut microbiota in patients with irritable bowel syndrome: a systemic review and meta-analysis

In the first stage, each model was constrained to obtain an optimal fit to the gene expression signature of the cell line by solving a Mixed Integer Linear Programming problem, via the integrative Metabolic Analysis Tool (iMAT) 32,33

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