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Long-standing active disease increases the risk of colorectal cancer, and severe cases can lead to life-threatening complications, including toxic megacolon and intestinal perforation (Rubin et al., 2025)

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Hormetins activate the Nrf2 pathway, upregulating the expression of genes encoding antioxidant enzymes, such as glutathione peroxidase and superoxide dismutase

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Sun Exposure: Ultraviolet (UV) radiation from the sun stimulates melanocytes, the pigment-producing cells in the skin, to produce more melanin