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The rs694539 variation has shown the significant associations with many noninfectious chronic diseases (NCDs), such as hyperhomocysteinemia [35], nonalcoholic steatohepatitis [36], congenital heart diseases [37], migraine [38], bipolar disorder [39], schizophrenia [40], epilepsy [41], and abdominal aortic diseases [42], and the rs1941404 variation has been reported to be associated with hyperlipidemia [30]

Environmental risk factors for gallbladder cancer: field-wide systematic review and meta-analysisClin Gastroenterol Hepatol 2024;S1542-3565(24)00866-8 [DOI] [PubMed] 56.Chang J S, Hsiao J R, Chen C H