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Specifically, ATF-4 enhances stress resistance and promotes longevity in worms by upregulating the transsulfuration enzyme CTH-2, increasing hydrogen sulfide (H 2 S) production (Statzer et al., 2022)

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Additionally, HOXC8 has been reported to be involved in liver fibrosis in a mouse model, where its expression is increased, and suppression of HOXC8 leads to reduced fibrosis 37

T cells are part of the cellular immune system, whereas B cells are part of the humoral immune system

Patchen ML, MacVittie TJ, Weiss JF (1990) Combined modality radioprotection: the use of glucan and selenium with WR-2721