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Insulin-like growth factor-I as a promoting factor for cerebellar Purkinje cell development
Mutations in several genes have been associated with monogenic forms of Parkinson's disease, including SNCA, LRRK2, Parkin, PINK1 , and DJ-1
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However, its effect in vivo is very likely not direct but due to its ability to modulate the cells antioxidant defense mechanisms
doi: 10.1152/ajpregu.00104.2006
