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Tumor Necrosis Factor (TNF) is a pivotal inflammatory mediator regulated by epigenetic mechanisms and microRNAs
Others have identified astrocytes as a target for the neuroprotective effects of UA, demonstrating effects on astrocytic glutathione and Nrf2, and providing further support for the involvement of UA in antioxidative processes 52
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[21] revealed that there is little global standardization of thromboembolism reporting and a low rate of acute COVID-19 vasculopathy detection, suggesting that current diagnostic methods for identifying pulmonary vascular disease may not be sufficient