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doi: 10.3389/fendo.2025.1722623 Received 11 October 2025 Revised 11 November 2025 Accepted 12 November 2025 Published 26 November 2025 Volume 16 - 2025 Edited by Roma Patel, Albert Einstein College of Medicine, United States Reviewed by Xue Xiaoyong, Beijing University of Chinese Medicine, China Updates Copyright 2025 Ling, Schultz, Knight, Shearn and Baumel-Alterzon