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It plays a critical role in detoxifying heavy metals and pollutants, synthesizing DNA, activating enzymes, and regulating various cellular processes

Moreover, the cytokine signatures have potential as biomarkers to differentiate the two types of IBD as CD primarily expresses Th1- and Th17-associated cytokines (IL-17, -23 and -32), whereas UC is an atypical Th2-with low IL-4 and high IL-5, -13, -15 and -33 [70]

In addition to infertility, many diseases are associated with PCOS, including endometrial cancer, type 2 diabetes, impaired glucose tolerance, metabolic syndrome, cardiovascular risk, non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH) (223)

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Additionally, at concentrations of 840 M, 13-HOA significantly suppressed TPA-induced anchorage-independent growth in JB6 epidermal cells by 70100%, and at 40 M, it inhibited AP-1 activity
