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ii) compared with the control groups, serum GSH-Px levels were significantly higher in the GSH groups, though there was notable heterogeneity between the studies (I 2 =96%)
Furthermore, the patients with OIPN are more likely to benefit from duloxetine than patients with a paclitaxel-induced neuropathy based on an exploratory responder analysis [182], which suggests that action of duloxetines pharmacodynamic effect may be tightly associated with specific molecular mechanisms underlying OIPN [183, 184]

M Romitti was supported in part by the Brazilian National Council for Scientific and Technological Development (CNPq
Multiple sequence alignment and motif identification Multiple sequence alignment was performed using ClustalW (Ver

10.1177/24725552211020668 41 ChoudharyN.GoyalR.JoshiS
