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Disruption of ATP availability causes deprived ion transport, leading to elevated intracellular Ca 2+ levels, activation of the Gardos channel, cellular dehydration, and diminished deformability (29, 30)

Rohatgi PR, Swisher SG, Correa AM, Wu TT, Liao Z, Komaki R, Walsh G, Vaporciyan A, Lynch PM, Rice DC , Roth JA, Ajani JA

The surface modification of the liposome with ligands (antibodies or peptides) ensures targeted delivery to dopaminergic neurons, which could improve their targeting capabilities and efficacy and reduce side effects

By affixing lactate groups to lysine residues, histone Kla directly connects metabolic fluctuations with the regulation of gene expression, hence connecting metabolic conditions to epigenetic regulation