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10.3390/ijms150712972 84

In addition, CR6-interacting Factor 1 (CRIF1), also known as growth arrest and DNA damage-inducible proteins-interacting protein 1 (GADD45GIP1), interacts with Neh2 domain and the C-terminal region containing Neh1 and Neh3 of NRF2 to promote NRF2 ubiquitylation and degradation in a redox-independent manner [22]

These compounds represent good leads for the future development of XO inhibitors

The proper function of the lens hinges on its transparency (MedlinePlus 2012)

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