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They assist in reestablishing immune homeostasis in the reproductive tract by promoting a shift in macrophage and T-cell phenotypes toward regulatory, which supports tolerance during implantation and avoids immune-mediated gamete injury

Cohen J, Nassau DE, Patel P, Ramasamy R

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In the case of a true allergic reaction to the intramuscular vitamin B12 supplement, alternative routes of administration (e.g., intrinsic factordependent enteral route) should be considered