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doi: 10.1016/j.neuint.2022.105311 276 Ferrara-RomeoIMartinezPSaraswatiSWhittemoreKGraa-CastroOThelma PoluhaLet al

CAR cells are the main producers of several cytokines and growth factors required for the maintenance of the HSC niche, including CXCL12, interleukin-7 (IL-7), macrophage colony-stimulating factor (M-CSF), and stem cell factor (SCF) (23, 574, 576)

Foxo3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis

Furthermore, the microvascular dysfunction and microclotting frequently observed in Long COVID patients create localized areas of tissue hypoxia (low oxygen)