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Insufficient human clinical data Most research on AOD-9604 has been conducted in animals or short-term human trials, making it difficult to determine its full long-term effects

In terms of future research directions, large-scale, randomized, placebo-controlled clinical trials must be conducted that fully consider the effects of potential confounding factors to clarify the long-term effects of SSRIs on male and female fertility, to assess the recovery of reproductive function after drug discontinuation, and to clarify their reversibility

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248 A small number of clinical studies have found that antioxidant vitamin E, CoQ10, and alpha-lipoic acid combined with polarized light are effective in controlling T2DM complications, including diabetic foot