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According to the World Alzheimers Disease Report 2021, there are currently around 50 million patients with AD worldwide

Therefore, in mice lacking the sEH gene, there is an increase in endogenous EET levels, but this increase leads to elevated 20-HETE levels, resulting in more severe kidney damage

Senescent cells are also characterized by reduced mitophagy, leading to the accumulation of dysfunctional mitochondria and a noticeable increase in mitochondrial presence within the cell, which may serve as another indicator of cellular senescence [25]

[85] Gardner CD, Oelrich B, Liu JP, et al

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