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Pernicious anemia is a very rare autoimmune disorder that does not allow for proper vitamin B12 absorption which ultimately leads individuals to have an irreversible deficiency in this vitamin

K.HongJ.-Y.LeeH.-J.et al (2018)

[38] Cost effectiveness [edit] A 2007 study found that the live vaccine is likely to be cost-effective in the US, projecting an annual savings of US$82 to US$103 million in healthcare costs with cost-effectiveness ratios ranging from US$16,229 to US$27,609 per quality-adjusted life year gained