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Description
To diagnose hepatic steatosis, it is necessary to demonstrate fat accumulation in more than 5% of hepatocytes on histopathological examination, in the absence of significant alcohol consumption or other causes of liver injury or steatosis, or to detect more than 5.6% fat using proton magnetic resonance spectroscopy (H-MRS) [19]
Nat Rev Immunol 19:503516 Rodriguez-Alonso R, Letoquart J, Nguyen VS, Louis G, Calabrese AN, Iorga BI, Radford SE, Cho SH, Remaut H, Collet JF (2020) Structural insight into the formation of lipoprotein-beta-barrel complexes

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Available online at: (Accessed August 27, 2025)

Canonical GPX4/glutathione (GSH) defense axis The canonical axis defending against ferroptosis is centered on the GPX4/GSH system (26)