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Patients with OH had a significantly higher rate of conversion to MSA

Elevations in plasma concentration due to enterohepatic recirculation are usually observed after a meal when bile containing drug is released into the duodenum and the drug is reabsorbed from the intestine (Kwon 2001)

Regulating blood sugar The Mayo Clinic notes that vitamin B6 may affect blood sugar levels and advises caution for people who have diabetes or low blood sugar

Cell Signal 19(4):672682 Crompton M (1999) The mitochondrial permeability transition pore and its role in cell death

Taking an expired supplement may mean that they are not getting enough of the vitamin